I've traveled with my ekkies. Nothing crazy. Just around 2-3 hours away for an overnight trip at the longest. Not that I wouldn't go farther, I've just never had an occasion where taking them farther has been an option.
As for your particular situation, it really depends. There are so many factors. Is your ekkie used to traveling in a car at all? (I'm assuming we're talking car travel, here.) How long is the drive? Will she get out time at her vacation destination?
If she's not used to driving about in a car, you can start taking her on shorter trips around your town. You know, to get her acclimated to the experience. Some birds, like Bixby and Maya, take to it like it's the most natural thing in the world. Others, like Jolly, really need to be acclimated. (He used to freak out and attempt to dodge every tree that he saw! Hahaha! It just never occurred to him that WE were the ones who were moving, not the trees that were hurtling our way. Poor thing. Lol)
If she gets freaked out on the trial runs, you may need more acclimation time than you have. But if she's copacetic, she just might be ready for a holiday trip.